GHK-Cu research peptide – GHK-Cu (glycyl-L-histidyl-L-lysine) is a naturally occurring

GHK-Cu

5.0 (2)

GHK-Cu (glycyl-L-histidyl-L-lysine) is a naturally occurring copper-binding tripeptide that drives collagen synthesis, skin repair and wound healing.

SkinAnti-Aging
In Stock

Total Price

฿800

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For research & laboratory use only. Not for human consumption.

Administration Route

Subcutaneous injection

Collagen Synthesis +70%

Upregulates COL1A1 and COL3A1 in fibroblast studies

Wound Healing

Attracts macrophages and fibroblasts to wound sites

Neuroprotection

Promotes BDNF expression and protects against neurodegeneration

Effect Timeline

Start — Week 2

Skin texture improvements begin; wound healing accelerated

Week 4

Collagen density visibly improved; fine lines reducing

Week 8

Significant skin thickness improvement; pigmentation evening

Week 12

Deep wrinkle reduction; skin elasticity restored

Mechanism of Action

GHK-Cu is a tripeptide that binds a copper(II) ion, and this copper complex is what makes it biologically active. In dermal fibroblasts it upregulates synthesis of collagen types I, III and VI and boosts decorin, the proteoglycan that organises collagen fibrils into ordered structure. It triggers VEGF and FGF release to drive angiogenesis at repair sites, and it attracts macrophages and fibroblasts that clean and rebuild wounded tissue. At the transcriptional level GHK-Cu behaves as a broad gene-expression modulator: microarray work shows it switches on genes tied to tissue remodelling and antioxidant defence while switching off genes linked to inflammation and cancer progression.

Scientific Research

1
GHK and GHK-Cu: Humankind's forgotten cure?

Annals of the New York Academy of Sciences (2015)

2
Copper peptide GHK-Cu in collagen synthesis and wound healing

Journal of Aging Research and Clinical Practice (2015)

Why Researchers Choose GHK-Cu

GHK-Cu is the best-characterised copper peptide in skin and regeneration research, valued because it pairs collagen-building activity with broad gene-expression control. It is studied wherever dermal repair, matrix remodelling and anti-ageing biology intersect:

  • Collagen synthesis and extracellular matrix remodelling studies
  • Wound healing and angiogenesis research protocols
  • Skin ageing and dermal fibroblast function investigations
  • Anti-inflammatory cytokine modulation studies
  • Gene expression profiling under copper peptide exposure
  • Neuroprotection research (NGF and BDNF upregulation)
  • Hair follicle stimulation and follicular biology investigations

Reconstitution and Storage

Reconstitution: use bacteriostatic water (1 to 2ml per vial); swirl gently until fully dissolved, do not shake. After reconstitution: keep refrigerated at 2-8°C and use within 28 days; do not freeze after reconstitution. Protect from direct light.

Dosing at a Glance

Route

Subcutaneous injection

Frequency

Once daily

Typical research dose

1–5 mg

Calculate dosage

Opens the calculator with this peptide preselected. Research reference only.

Product FAQs

Customer Reviews

5.0 (2)

Amazing product, and the shipping was very quick!

Tom
2026-03-13

I have been pinning 0.1ml every day for 6 weeks, and the collagen production is off the charts. I supplement with collagen edibles and drink a lot of broth, and people around me are commenting that I have a very fresh glow to my skin. Really recommend GHK-Cu!

Adriana
2025-01-04

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