Not for human use, for research purposes only
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GHK-Cu - GHK-Cu (glycyl-L-histidyl-L-lysine copper complex) is a natu

GHK-Cu

5.0 (2)

GHK-Cu (glycyl-L-histidyl-L-lysine copper complex) is a naturally occurring copper-binding tripeptide (Gly-His-Lys) that binds Cu(II) with high affinity.

DermalCellular
In Stock

1 vial · 50 mg total

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Total Price

฿800

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For research & laboratory use only. Not for human consumption.

Shipping: free within Thailand, ฿700 worldwide. Added at checkout. Delivery times & countries

Cell Migration Models

Macrophage and fibroblast migration studied in cell models

Neuronal Cell Models

NGF and BDNF expression studied in neuronal cell models

Copper-Binding Tripeptide

Gly-His-Lys with high affinity for Cu(II)

Mechanism of Action

GHK-Cu is a tripeptide (Gly-His-Lys) that binds a copper(II) ion, and this copper complex is the studied form. In dermal fibroblast cultures it upregulates synthesis of collagen types I, III and VI and of decorin, the proteoglycan that organises collagen fibrils. It is reported to induce VEGF and FGF release and to attract macrophages and fibroblasts in cell migration models. At the transcriptional level GHK-Cu is described as a broad gene-expression modulator: microarray work shows altered expression of genes involved in matrix remodelling, antioxidant defence and inflammation signalling.

About GHK-Cu

GHK-Cu is the copper(II) complex of the tripeptide glycyl-L-histidyl-L-lysine (Gly-His-Lys). The tripeptide occurs naturally in human plasma, saliva and other tissues, and it binds Cu(II) with high affinity. The copper complex is the form studied in the laboratory.

Research Areas

GHK-Cu is investigated in the following areas of laboratory research:

  • Collagen and decorin synthesis and extracellular matrix remodelling in fibroblast cultures
  • Angiogenesis signalling (VEGF and FGF release)
  • Macrophage and fibroblast migration in cell models
  • Cytokine signalling (TNF-alpha and IL-6)
  • Gene expression profiling under copper peptide exposure
  • NGF and BDNF expression in neuronal cell models
  • Copper(II) chelation chemistry

Storage

Lyophilised vials: store at -20°C, protected from light.

For research purposes only. Not for human consumption.

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Customer Reviews

5.0 (2)

Very good product, fast delivery. Recommended Seller

Mr. S. Verified
2026-09-13

Amazing product, and the shipping was very quick!

Tom
2026-03-13

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