TB-500
TB-500 is a synthetic fragment of Thymosin Beta-4, a 43-amino-acid peptide, that binds G-actin and is studied in actin dynamics and cell migration research.
1 vial · 10 mg total
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Total Price
฿1600
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G-Actin Binding
Binds free G-actin monomers and regulates actin polymerisation in cell models
Cardiac Cell Models
Studied in cardiomyocyte and epicardial progenitor cell models
Cytokine Signalling
Reported to reduce NF-kB signalling and pro-inflammatory cytokine output in cell models
Mechanism of Action
About TB-500
TB-500 is a synthetic peptide that reproduces the active region of Thymosin Beta-4 (TB4), a 43-amino-acid peptide expressed in almost every cell type. The fragment is described as corresponding to amino acids 17-23 (LKKTETQ), the region associated with actin binding.
Research Areas
TB-500 and Thymosin Beta-4 are investigated in the following areas of laboratory research:
- Actin binding and cytoskeleton dynamics
- Cell migration assays
- Cardiac cell models, including epicardial progenitor cells and cardiomyocytes
- Angiogenesis and endothelial progenitor cell models
- NF-kB and cytokine signalling in cell studies
- Oligodendrocyte differentiation and myelination in cell models
TB-500 and BPC-157: Mechanism Comparison
TB-500 and BPC-157 are different compounds with different sequences, origins and signalling pathways:
| Property | BPC-157 | TB-500 |
|---|---|---|
| Angiogenesis signalling | VEGF upregulation | MMP-2, VEGF |
| Cell migration | FAK-paxillin | Actin sequestration |
A kit containing one vial of each compound is listed as Wolverine Stack.
Storage
Lyophilised vials: store at -20°C, protected from light.
For research purposes only. Not for human consumption.
Compound comparisons are listed in the comparison section.
Product FAQs
Listed in Blends
Tissue Repair Blend
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