Melanotan 2
Melanotan 2 (MT-II) is a synthetic cyclic lactam analogue of alpha-MSH with agonist activity at the MC1R, MC3R, MC4R and MC5R receptors. Research compound.
1 vial · 10 mg total
Checking availability…
Total Price
฿800
& more more: Bancontact, Open Banking, Cash App, Afterpay, more coinsCrypto −5%Encrypted checkoutFor research & laboratory use only. Not for human consumption.
Shipping: free within Thailand, ฿700 worldwide. Added at checkout. Delivery times & countries
Half-Life
~33 minutes
Rapid Tanning
Cyclic alpha-MSH analogue produces deep tan in 7-14 days
Four Receptor Subtypes
Binds MC1R, MC3R, MC4R and MC5R without selectivity
Cyclic Lactam Structure
cyclo[Nle4,Asp5,D-Phe7,Lys10]-alpha-MSH(4-10)
Mechanism of Action
Scientific Research
Peptides (2000)
Urology (2000)
Why Researchers Choose Melanotan 2
Melanotan 2 (MT-II) is the reference tool compound for the melanocortin system, because a single cyclic alpha-MSH analogue engages four receptors at once. That breadth makes it a frequent subject across several research areas:
- UV-independent melanogenesis and photoprotective pigmentation via MC1R
- MC4R signalling in sexual motivation and erectile function
- MC3R and MC4R signalling in energy-homeostasis models
- Receptor-selectivity comparisons against the linear analogue PT-141 (bremelanotide)
- Structure-activity work on cyclic versus linear melanocortin peptides
Melanotan 2 Receptor Pharmacology
The four melanocortin receptors relevant to MT-II research and the effect each one mediates:
| Receptor | Primary Location | MT-II Effect |
|---|---|---|
| MC1R | Melanocytes, skin | Melanogenesis, photoprotection |
| MC3R | Hypothalamus, limbic | Energy balance, anti-inflammatory |
| MC4R | Hypothalamus, brainstem, spinal cord | Central energy homeostasis, reproductive signalling |
| MC5R | Exocrine glands, adrenal cortex | Exocrine secretion |
MC1R is expressed on melanocytes, while MC3R and MC4R are central receptors. The absence of receptor selectivity is the defining pharmacological feature of MT-II.
Scientific Significance
Melanotan 2 was the compound that established MC4R as the central receptor for mammalian sexual function. A 1998 Science study showed that MT-II induced spontaneous erections in MC4R-expressing rodents and that knocking out MC4R abolished the effect. That finding led directly to three developments:
- The design of PT-141 (bremelanotide) as a selective MC4R agonist
- PT-141’s FDA approval as Vyleesi for hypoactive sexual desire disorder (HSDD)
- Sustained MC4R research across obesity, sexual dysfunction and cardiovascular regulation
As the molecule that opened up MC4R biology, Melanotan 2 remains a reference compound in melanocortin receptor research. It is not an approved medicine.
Reconstitution and Storage
Reconstitution: use bacteriostatic water; swirl gently until dissolved, do not shake. After reconstitution: keep refrigerated (2-8°C), protect from direct light, and use within 30 days.
For research purposes only. Not for human consumption.
Vial & calculation
Calculate concentration and volume from the labelled amount, your final solution volume and a target amount you provide.
Open calculator for Melanotan 2Current product variants are listed in the calculator. No personal dose is selected for you.
Product FAQs
Customer Reviews
Very happy with the results. Visiting Pattaya for a few weeks and got an amazing tan.
Good, real and works
Been a solid bronze for a year. Potent MT2. Highly recommend, ordered many times. Glowing skin and a noticeable boost in libido.
Works great. And the service is the best.
Works great, it's legit. Delivery in less than 2 days to Pathum Thani. I recommend taking cetirizine 30 minutes before pinning to avoid nausea.
I arrived from Russia very fair-skinned and was badly sunburnt after my first week here. I tried another company's Melanotan and had to stop using it after a few days because it made me nauseous and the results were poor. A friend recommended Milo Lab, and after purchasing this product, the results were amazing. My skin was a golden brown, I had no side effects, and overall I felt and looked fantastic. I highly recommend Milo Lab for this product - the service and packaging were also very professional, so I could tell it's not a cheap backyard operation. From Russia with love, Zhenya.
Fantastic quality for this MT2! 4 days delivery after payment.
