Tesofensine (development code NS2330) is a small-molecule triple monoamine reuptake inhibitor acting at the dopamine, noradrenaline and serotonin transporters. It is supplied in capsule form for laboratory research, not as a peptide.

What is its half-life?

Approximately nine days in published pharmacokinetic studies, among the longest of the monoamine reuptake inhibitors.

How is it supplied and verified?

In sealed capsules at the stated content per unit, with a certificate of analysis reporting purity and identity, available on request before ordering.

How should it be stored?

Sealed, dry, at room temperature and protected from light and humidity.

Tesofensine

Name: Tesofensine
Brand: Milo-Lab
Availability: InStock
Rating: 5 (1 reviews)

5.0 (1)

Tesofensine (NS2330) is a small-molecule triple monoamine reuptake inhibitor at the DAT, NET and SERT transporters. Research compound.

MetabolicMitochondrial

In Stock

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1 capsule · 500 mcg total

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Total Price

฿3400

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For research & laboratory use only. Not for human consumption.

Shipping: free within Thailand, ฿700 worldwide. Added at checkout. Delivery times & countries

Half-Life

~9 days

Mechanism of Action

Tesofensine (development code NS2330) is a centrally-acting triple monoamine reuptake inhibitor that blocks the presynaptic transporters for noradrenaline (NET), dopamine (DAT) and serotonin (SERT). Blocking reuptake raises the synaptic concentration of all three monoamines. Its plasma half-life of roughly nine days is among the longest in this compound class. Unlike the incretin peptides it is a small molecule.

Scientific Research

Effect of tesofensine on bodyweight loss, body composition, and quality of life in obese patients: a randomised, double-blind, placebo-controlled trial

The Lancet (2008)

Why Researchers Choose Tesofensine

Tesofensine (NS2330) is a small-molecule triple monoamine reuptake inhibitor, which makes it a research tool wherever monoamine transporter pharmacology is studied and compared with peptide receptor pharmacology:

Triple monoamine (noradrenaline, dopamine, serotonin) reuptake pharmacology
Binding at the NET, DAT and SERT transporters
Monoamine transporter selectivity profiling
Comparison of small-molecule transporter inhibition with peptide receptor agonist mechanisms

Storage

Storage: keep capsules cool, dry and away from direct light and moisture; keep tightly sealed and away from heat.

For research purposes only. Not for human consumption.

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Customer Reviews

5.0 (1)

Milo-Lab is simply the best: purest product and great customer support. Highly recommended.

Daniel K.

2026-10-26

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