Retatrutide - Retatrutide (LY3437943) is an investigational peptide bindin
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Retatrutide

4.9 (14)

Retatrutide (LY3437943) is an investigational peptide binding the GLP-1, GIP and glucagon receptors. Research compound, not an approved medicine.

MetabolicEndocrine
In Stock

1 vial · 10 mg total

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Total Price

฿2800

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For research & laboratory use only. Not for human consumption.

Shipping: free within Thailand, ฿700 worldwide. Added at checkout. Delivery times & countries

Half-Life

6 days

Triple Receptor Agonist

Binds GLP-1, GIP and glucagon receptors from one molecule

Hepatic Glucagon Signalling

Glucagon receptor activation in hepatic tissue

Six-Day Half-Life

Fatty-acid acylation and reversible albumin binding

Mechanism of Action

Retatrutide is a single peptide with agonist activity at three receptors: GLP-1, GIP and glucagon. GLP-1 and GIP are incretin receptors, both class B G-protein coupled receptors signalling through cAMP. The glucagon receptor is the third target and distinguishes retatrutide from dual agonists such as tirzepatide and from single GLP-1 agonists such as semaglutide. Its plasma half-life of roughly six days derives from fatty-acid acylation and reversible albumin binding.

Scientific Research

Why Researchers Choose Retatrutide

Retatrutide is the first triple-receptor agonist to reach late-stage metabolic research. It is studied in:

  • Tri-receptor pharmacology and additive receptor-engagement studies
  • Triple-receptor pharmacology beyond GLP-1 and GLP-1/GIP agonists
  • Energy-expenditure and thermogenesis pathway investigations
  • Hepatic lipid metabolism and non-alcoholic steatohepatitis (NASH) research
  • Metabolic flexibility and substrate-utilisation studies

How Retatrutide Works

Retatrutide activates three metabolic receptors simultaneously: GLP-1, GIP and glucagon. The GLP-1 and GIP arms engage the same incretin receptors as tirzepatide. The addition of glucagon receptor activation is what sets it apart, adding a third signalling pathway, so retatrutide engages three receptor systems rather than one or two. The simultaneous GLP-1 signal is the pharmacological counterpart to glucagon receptor activation, the pharmacological basis of the triple-agonist design.

Retatrutide vs. Semaglutide and Tirzepatide

Retatrutide is a GLP-1, GIP and glucagon triple agonist, one step beyond tirzepatide (dual GLP-1/GIP) and semaglutide (GLP-1 only). The added glucagon axis is the pharmacological difference between the three. No direct head-to-head trial has been published and Phase 3 studies are ongoing.

Reconstitution and Storage

Reconstitution: use bacteriostatic water (1 to 2ml per vial); swirl gently until fully dissolved, do not shake. After reconstitution: keep refrigerated (2-8°C), use within 28 days, do not freeze, and protect from direct light.

Ordering Retatrutide in Thailand

Choose the required format from the options on this page and check current price and availability before ordering. For sourcing background, read our Retatrutide Thailand guide.

For Bangkok, Phuket, Koh Samui and other Thai destinations, see how to order research peptides in Thailand. Enter a complete delivery address and a reachable Thai telephone number. Payment options are shown at checkout; processing and delivery estimates are explained in the shipping policy.

Vial & calculation

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Product FAQs

Customer Reviews

4.9 (14)

It went better than I'd hoped and your new ordering process works perfectly. The retatrutide is an excelent product.

Jim Verified
2026-10-03

I’ve been using Retratrutide for two weeks now. It 100% suppresses appetite and helps with calorie control. No side effects as of far. Overall: good product and customer service.

AvZ Verified
2026-09-24

Life changing peptide, completely eliminates food noise and allows you to focus on nutritious healthy options

Patrick Verified
2026-09-21

Being taking reta 5 months with no exercise at all with a busy lifestyle I managed to drop Eighteen kilograms

Steven Verified
2026-09-12

Very simple process and order arrived as expected.

Darren Verified
2026-09-08

very good product High-quality

mark Verified
2026-09-04

Ordered Reta after I already got HGH from him. Showed up in a couple days in Bangkok, no cold pack, vial was fine. Started low and went to 4mg. Hunger quieter, nothing nasty. Easy local order. I’ll use him again.

Ry Verified
2026-09-02

Retatrutide: The results have been highly noticeable even at a conservative starting point. I observed significant hunger suppression using only a 1mg dose. Side Effects: The only notable side effect at this 1mg dosage was a slight headache, which was manageable and didn't interfere significantly with the process.

Mea Verified
2026-08-31

Used for weight loss. It works as advertised. Using the minimal dosage have lost 21 pounds in 90 days

Donald Verified
2026-08-27

Fast delivery, great support. The product looks clean and now needs to be tested. Reconstitution went smoothly.

Mr. R. Verified
2026-08-26

I work perfectly lose 10kg

Franck Verified
2026-08-25

Excellent quality. Followed the useage guide provided on the website. Noticeable reduction in appetite. The easiest cut I’ve ever done dropped 8kg bodyfat and had very little side effects. A tiny bit of digestive discomfort first few weeks that’s it. Highly recommend and the customer service here is fantastic.

Matt Verified
2026-08-24

Excellent product. I have been unable to exercise after a motorbike accident and have still been keeping trim. I can't weigh myself until I go to the gym, but I've had to add another hole to my shorts belt. I now take 2mg a week with no nausea. Painless injections with BAC water, much better than saline, which causes irritation at the injection site.

Stuart B.
2026-03-18

Crazy good. Taking a moderately low dose of 1mg weekly and have zero desire to eat anything bad for me. Sticking to a 700 calorie deficit with ease. Super fast shipping and great owner too!

Matthew
2026-01-27

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